Jessica Shantha, MD, MS

Assoc HS Clinical Professor
Proctor Foundation

Dr. Shantha worked from 2015-2017 in West Africa, where the magnitude of the challenges of treating uveitis and ocular inflammation due to resource requirements and disease complexity become apparent. Her career goal is to impact the blinding consequences of unrecognized or untreated uveitis in resource-limited settings. Dr. Shantha is most proud of the ability to advocate for the thousands of Ebola virus survivors that need eye care and routine screenings. Additionally, she has been able to impart perspectives and build capacity related to uveitis management in resource-limited settings via regional seminars, education, and mentorship. Through multiple ongoing studies and longstanding partnerships, Dr. Shantha is dedicated to the work towards vision health equity and access in the West Africa region. Dr. Shantha is continuing to explore her academic and clinical interests that include infectious and non-infectious uveitis, emerging pathogen discovery, and addressing clinical and research gaps within uveitis and retinal disease in international health care settings.

Publications: 

Childhood vision impairment and blindness in West Africa: public health measures and implications for systemic health.

Frontiers in medicine

Yeh C, Huang C, Huang Y, Hartley CD, Fashina T, Ashby N, Miller C, Shantha JG, Justin GA, Chan RVP, Mattia JG, Vandy MJ, Harrison-Williams L, Mustapha J, Mwanza JC, Yeh S

Stromal Keratitis Associated With CMV Anterior Uveitis.

Cornea

Pisitpayat P, Mentreddy A, Pekmezci M, Hwang D, Shantha J, Benador-Shen C, Terry M, Pothikamjorn T, Gonzales J

Variations in Electronic Health Record-Based Definitions of Diabetic Retinopathy Cohorts: A Literature Review and Quantitative Analysis.

Ophthalmology science

Chen JS, Copado IA, Vallejos C, Kalaw FGP, Soe P, Cai CX, Toy BC, Borkar D, Sun CQ, Shantha JG, Baxter SL

Towards an Imaging-centric Definition of Non-paraneoplastic Autoimmune Retinopathy.

Retina (Philadelphia, Pa.)

Xu LT, Zheng A, Shantha JG, Yeh S, Yan J, Hubbard GB, Patel PS, Waltuck J, O'Keefe G, Jain N

Retinopathy Associated With Ritonavir Treatment for HIV Infection: A Case Series Reappraisal in the COVID-19 Era.

Journal of VitreoRetinal Diseases

Nguyen NV, Kim L, Collins LF, Ofotokun I, Fernandes A, Yeh S, Shantha J

Visual acuity and vision-related quality of life outcomes following cataract surgery in Ebola virus disease survivors.

Global journal of cataract surgery and research in ophthalmology

Taraborelli D, Thomas JJ, Kim L, Fashina T, Hayek B, Mattia JG, Vandy M, Sugar E, Crozier I, Yeh S, Shantha JG

Anxiety and depression in patients with uveitis: a comprehensive review of observational studies.

Current opinion in ophthalmology

Choo CH, Gonzales J, Shantha JG

Clinical characteristics and Aetiology of Uveitis in a Viral Haemorrhagic Fever Zone.

Research square

Balendra S, Williams L, Mustapha J, Koroma Z, Kamara A, Conteh O, Kanu T, Saradugu B, Kamara S, Ward L, Wang H, Fashina T, Koroma S, Shantha J, Yeh S, Kennedy A

Isolated Ocular Mpox without Skin Lesions, United States.

Emerging infectious diseases

Nguyen MT, Mentreddy A, Schallhorn J, Chan M, Aung S, Doernberg SB, Babik J, Miles K, Yang K, Lydon E, Minter DJ, Gonzales J, Shantha J, Doan T, Seitzman GD

Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.

Ocular immunology and inflammation

Liao A, Fajoles-Vasseneix C, Rali A, Ward L, Fernandes A, Patel PS, O'Keefe G, Shantha JG, Yeh S

Therapeutic Drug Monitoring in Noninfectious Uveitis.

JAMA ophthalmology

Shantha J, Acharya NR

Global Ophthalmic Health Initiatives in Ebola and Emerging Infectious Disease Outbreaks: Implications for Vision Health Systems, Program Implementation, and Disease Surveillance.

International ophthalmology clinics

Huang Y, Mustapha J, Harrison-Williams L, Fashina T, Randleman C, Ifantides C, Shantha JG, Yeh S

Research Partnerships and Guidance in Academic Global Ophthalmology.

International ophthalmology clinics

Ehrlich JR, Shantha JG, Mathenge C, Fashina T, Cole E, Al-Khaled T, Ravilla T, Chan RVP, Yeh S, American Academy of Ophthalmology Task Force on Academic Global Ophthalmology

COVID-19 and the eye: Systemic and laboratory risk factors for retinopathy and detection of tear film SARS-CoV-2 RNA with a triplex RT-PCR assay.

PloS one

Shantha JG, Fashina T, Stittleburg V, Randleman C, Ward L, Regueiro M, Krakow D, Linderman SL, Drews-Botsch C, Ahmed R, Waggoner J, Yeh S

Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey.

Communications biology

Worwa G, Cooper TK, Yeh S, Shantha JG, Hischak AMW, Klim SE, Byrum R, Kurtz JR, Anthony SM, Aiosa NM, Ragland D, Lee JH, Claire MS, Davis C, Ahmed R, Holbrook MR, Kuhn JH, Saphire EO, Crozier I

Current Landscape of Uveitis Specialists in the United States.

Journal of academic ophthalmology (2017)

Tsui E, Crowell EL, Gangaputra S, Moussa K, Shantha JG, Shusko AJ, Thompson IA, Pham DC, Jackson NJ, Venkat AG

Relapse and Remission in Children With Chronic Noninfectious Uveitis Treated With Methotrexate.

The Journal of rheumatology

McCracken C, Shantha JG, Yeh S, Jenkins K, Rouster-Stevens KA, Lambert SR, Prahalad S, Drews-Botsch C, Angeles-Han ST

Bilateral anterior and intermediate uveitis in SARS-CoV-2 associated multisystem inflammatory syndrome in a pediatric patient.

Pediatric rheumatology online journal

Shantha J, Reddy AK, Sura A, Tsang A, Moussa K, Acharya N, Gonzales J, Doan T

Refractive Outcomes of Combined Cataract Surgery and Vitrectomy Compared to Cataract Surgery Alone.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde

Kokame GT, Tanji TT, Yanagihara RT, Shantha JG, Nirwan RS, Tanji TM

Prevalence of Epstein-Barr Virus in Patients with Intraocular Inflammation.

Ocular immunology and inflammation

Moussa K, Gonzales JA, Shantha J, Acharya NR, Doan T

Comprehensive Assessment of Quality of Life, Functioning, and Mental Health in Children With Juvenile Idiopathic Arthritis and Noninfectious Uveitis.

Arthritis care & research

McDonald J, Cassedy A, Altaye M, Andringa J, Cooper AM, Drews-Botsch C, Engelhard G, Hennard T, Holland GN, Jenkins K, Lambert SR, Lipscomb J, McCracken C, McCurdy DK, Mwase N, Prahalad S, Shantha J, Stahl E, Utz VM, Walker AA, Yeh S, Angeles-Han ST

Ophthalmic sequelae and psychosocial impact in pediatric ebola survivors.

EClinicalMedicine

Shantha JG, Canady D, Hartley C, Cassedy A, Miller C, Angeles-Han ST, Harrison-Williams LCM, Vandy MJ, Weil N, Bastien G, Yeh S

Case Report: Delayed Onset Multi-Organ Toxicities in a Melanoma Patient Achieving Complete Response to BRAF/MEK Inhibition.

Frontiers in oncology

Knochelmann HM, Ware MB, Rali A, Linderman S, Shantha JG, Lawson DH, Yushak M, Swerlick R, Paulos CM, Yeh S, Kudchadkar R

Risk Factors for Retinal Detachment in Acute Retinal Necrosis.

Ophthalmology. Retina

Bavinger JC, Anthony CL, Lindeke-Myers AT, Lynch S, Xu LT, Barnett J, Levine D, Patel P, Shah R, Jain N, Rao P, Hendrick A, Cribbs BE, Yan J, Hubbard GB, Shantha JG, O'Keefe GD, Yeh S

In office management of optic capture of scleral fixated posterior chamber intraocular lenses.

American journal of ophthalmology case reports

Kokame GT, Card K, Pisig AU, Shantha JG

Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma.

International journal of retina and vitreous

Anthony CL, Bavinger JC, Shantha JG, O'Keefe GD, Pearce WA, Voloschin A, Grossniklaus HE, Yeh S

INVOLUTION OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION AFTER ENDOPHTHALMITIS.

Retinal cases & brief reports

Kokame GT, Yannuzzi NA, Shantha JG, Yamane M, Relhan N, Gross J, Ryan EH, Flynn HW

Uveitis in Children and Adolescents.

Rheumatic diseases clinics of North America

Chang MH, Shantha JG, Fondriest JJ, Lo MS, Angeles-Han ST

Cytopathology of Vitreous Specimens in Acute Retinal Necrosis.

Ocular immunology and inflammation

Hojjatie SL, Shantha JG, O'Keefe GD, Kraft CS, Voloschin A, Grossniklaus H, Yeh S

Implementation of the Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) study: Lessons learned for vision health systems strengthening in Sierra Leone.

PloS one

Shantha JG, Crozier I, Kraft CS, Grant DG, Goba A, Hayek BR, Hartley C, Barnes KG, Uyeki TM, Schieffelin J, Garry RF, Bausch DG, Farmer PE, Mattia JG, Vandy MJ, Yeh S, EVICT Study Investigators

Assessment of retinal microvascular health by optical coherence tomography angiography among persons with HIV.

AIDS (London, England)

Collins LF, Shantha JG, Nesper PL, Sheth AN, Fawzi AA, Yeh S, Ofotokun I

Update on biologic therapies for juvenile idiopathic arthritis-associated uveitis.

Annals of eye science

Thomas J, Kuthyar S, Shantha JG, Angeles-Han ST, Yeh S

Retinopathy and Systemic Disease Morbidity in Severe COVID-19.

Ocular immunology and inflammation

Shantha JG, Auld SC, Anthony C, Ward L, Adelman MW, Maier CL, Price KW, Jacob JT, Fashina T, Randleman C, Xu LT, Barnett J, Sadan O, Kandiah PA, Varkey JB, Kraft CS, Rouphael N, Linderman S, Ahmed R, Drews-Botsch C, Waggoner JJ, Weinmann M, Murphy DJ, Yeh S, Emory COVID-19 Quality and Clinical Research Collaborative

Varicella zoster virus anterior uveitis complicated by thalamic stroke.

Journal of ophthalmic inflammation and infection

Anthony CL, Costarides AP, Yeh S, Shantha JG

World Health Organization High Priority Pathogens: Ophthalmic Disease Findings and Vision Health Perspectives.

Pathogens (Basel, Switzerland)

Kuthyar S, Anthony CL, Fashina T, Yeh S, Shantha JG

Long-term Management of Panuveitis and Choroidal Mass Associated with Rosai Dorfman Disease with Pegylated Interferon.

Ocular immunology and inflammation

Kim L, Bavinger JC, Shantha JG, Costarides A, Grossniklaus HE, Yeh S

Posterior Segment Ophthalmic Manifestations in Ebola Survivors, Sierra Leone.

Ophthalmology

Berry DE, Bavinger JC, Fernandes A, Mattia JG, Mustapha J, Harrison-Williams L, Teshome M, Vandy MJ, Shantha JG, Yeh S, Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study Investigators

Efficacy and Safety Outcomes of Cataract Surgery in Survivors of Ebola Virus Disease: 12-Month Results From the PREVAIL VII Study.

Translational vision science & technology

Eghrari AO, Shantha JG, Ross RD, Ryn CV, Crozier I, Hayek B, Gradin D, Roberts B, Prakalapakorn SG, Amegashie F, Nishant K, Singh G, Dolo R, Fankhauser J, Burkholder B, Pettitt J, Gross R, Brady T, Dighero-Kemp B, Reilly C, Hensley L, Higgs E, Yeh S, Bishop RJ

Ophthalmic manifestations and vision impairment in Lassa fever survivors.

PloS one

Li AL, Grant D, Gbakie M, Kanneh L, Mustafa I, Bond N, Engel E, Schieffelin J, Vandy MJ, Yeh S, Shantha JG

Outcomes of Infectious Endophthalmitis in Patients with Systemic Antibiotic Allergies to Penicillins, Cephalosporins, or Vancomycin.

Ophthalmology. Retina

Meyer BI, Berry DE, Cribbs BE, Hendrick A, Jain N, Hubbard GB, O'Keefe G, Patel PS, Shantha JG, Yan J, Yeh S, Rao P

Systemic Lupus Erythematosus-associated Retinal Vasculitis Treated with Adalimumab.

Ocular immunology and inflammation

Kuthyar S, Barnes AC, Bhawal J, Christiansen J, Shantha JG, Yeh S

Ebola, COVID-19, and emerging infectious disease: lessons learned and future preparedness.

Current opinion in ophthalmology

Bavinger JC, Shantha JG, Yeh S

Ophthalmic and psychosocial sequelae in Ebola virus disease survivors: ongoing need for health systems strengthening across disciplines.

Expert review of anti-infective therapy

Canady D, Weil NC, Miller C, Shantha JG, Bastien G, Yeh S

SARS-CoV-2 and the Eye: Implications for the Retina Specialist from Human Coronavirus Outbreaks and Animal Models.

Journal of VitreoRetinal Diseases

FRCOphth AK, Shantha JG, Olivia Li JP, Faia LJ, Hartley C, Kuthyar S, Albini TA, Wu H, Chodosh J, Ting DSW, Yeh S

Outcomes of Combination Systemic and Intravitreal Antiviral Therapy for Acute Retinal Necrosis.

Ophthalmology. Retina

Debiec MR, Lindeke-Myers AT, Shantha JG, Bergstrom CS, Hubbard GB, Yeh S

Approach to Cataract Surgery in an Ebola Virus Disease Survivor with Prior Ocular Viral Persistence.

Emerging infectious diseases

Wells JR, Crozier I, Kraft CS, Sexton ME, Hill CE, Ribner BS, Bavari S, Palacios G, Pearce WA, Van Gelder R, Grossniklaus H, Cazares L, Zeng X, Shantha JG, Yeh S

Toxoplasmosis chorioretinitis mimicking acute retinal necrosis associated with local corticosteroid.

International journal of retina and vitreous

Crosson JN, Kuthyar S, Shantha JG, Debiec MR, Laird PW, Hwang CS, Grossniklaus HE, Yeh S

Preparedness among Ophthalmologists: During and Beyond the COVID-19 Pandemic.

Ophthalmology

Olivia Li JP, Shantha J, Wong TY, Wong EY, Mehta J, Lin H, Lin X, Strouthidis NG, Park KH, Fung AT, McLeod SD, Busin M, Parke DW, Holland GN, Chodosh J, Yeh S, Ting DSW

Successful Treatment of Full-Thickness Macular Hole in Polypoidal Choroidal Vasculopathy with Anti-VEGF Therapy.

Journal of VitreoRetinal Diseases

Lindeke-Myers A, Kokame GT, Yeh S, Shantha J

Update on the Management of Acute Retinal Necrosis.

Ophthalmic surgery, lasers & imaging retina

Li AL, Fine HF, Shantha JG, Yeh S

Letermovir for the Management of Cytomegalovirus-associated Uveitis.

Ocular immunology and inflammation

Tsui E, Gonzales JA, Shantha JG, Acharya N, Doan T

Update on the management of uveitis in children: an overview for the clinician.

Expert review of ophthalmology

Kim L, Li A, Angeles-Han S, Yeh S, Shantha J

Strength of Association between Pentosan Polysulfate and a Novel Maculopathy.

Ophthalmology

Hanif AM, Shah R, Yan J, Varghese JS, Patel SA, Cribbs BE, O'Keefe G, Hendrick AM, Shantha JG, Hubbard GB, Patel PS, Rao P, Yeh S, Jain N

Association of Ocular Inflammation and Rubella Virus Persistence.

JAMA ophthalmology

Gonzales JA, Hinterwirth A, Shantha J, Wang K, Zhong L, Cummings SL, Qian Y, Wilson MR, Acharya NR, Doan T

Development of a screening eye clinic for Ebola virus disease survivors: Lessons learned and rapid implementation at ELWA Hospital in Monrovia, Liberia 2015.

PLoS neglected tropical diseases

Shantha JG, Hayek BR, Crozier I, Gargu C, Dolo R, Brown J, Fankhauser J, Yeh S

Capnocytophaga Keratitis: Clinical Presentation and Use of Metagenomic Deep Sequencing for Diagnosis.

Cornea

Seitzman GD, Thulasi P, Hinterwirth A, Chen C, Shantha J, Doan T

Ocular manifestations of bartonellosis.

Current opinion in ophthalmology

Mabra D, Yeh S, Shantha JG

CYTOMEGALOVIRUS RETINITIS ASSOCIATED WITH OCCLUSIVE VASCULOPATHY IN AN ELDERLY, HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE MAN.

Retinal cases & brief reports

Moussa K, Doan T, Stewart JM, Shantha J, Gonzales J, Acharya N, Cunningham ET

Clinical Manifestations and Pathogenesis of Uveitis in Ebola Virus Disease Survivors.

Ocular immunology and inflammation

Yeh S, Shantha JG, Hayek B, Crozier I, Smith JR

Blurry Vision and Eye Pain After Pterygium Surgery.

JAMA ophthalmology

Moussa K, Shantha J, Schallhorn JM

Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Reverse Transcription-Polymerase Chain Reaction and Cataract Surgery Outcomes of Ebola Survivors in Sierra Leone.

EBioMedicine

Shantha JG, Mattia JG, Goba A, Barnes KG, Ebrahim FK, Kraft CS, Hayek BR, Hartnett JN, Shaffer JG, Schieffelin JS, Sandi JD, Momoh M, Jalloh S, Grant DS, Dierberg K, Chang J, Mishra S, Chan AK, Fowler R, O'Dempsey T, Kaluma E, Hendricks T, Reiners R, Reiners M, Gess LA, ONeill K, Kamara S, Wurie A, Mansaray M, Acharya NR, Liu WJ, Bavari S, Palacios G, Teshome M, Crozier I, Farmer PE, Uyeki TM, Bausch DG, Garry RF, Vandy MJ, Yeh S

Reply.

Ophthalmology

Shantha JG, Crozier I, Hayek BR, Bruce BB, Fankhauser J, Yeh S

Combination nivolumab- and cabiralizumab-associated acute bilateral anterior and posterior scleritis and anterior uveitis.

American journal of ophthalmology case reports

Gonzales JA, Shantha J, Acharya NR

Spectral-Domain Optical Coherence Tomography Angiography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde

de Carlo TE, Kokame GT, Shantha JG, Lai JC, Wee R

Polypoidal Choroidal Vasculopathy in Highly Myopic Eyes with Elongated Axial Length.

The open ophthalmology journal

Kokame GT, Tom ES, Shantha JG, Kaneko KN

Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas.

The British journal of ophthalmology

Gonzales J, Doan T, Shantha JG, Bloomer M, Wilson MR, DeRisi JL, Acharya N

An update on ocular complications of Ebola virus disease.

Current opinion in ophthalmology

Shantha JG, Crozier I, Yeh S

Ophthalmic Manifestations and Causes of Vision Impairment in Ebola Virus Disease Survivors in Monrovia, Liberia.

Ophthalmology

Shantha JG, Crozier I, Hayek BR, Bruce BB, Gargu C, Brown J, Fankhauser J, Yeh S

Ebola virus disease and the eye.

Current opinion in ophthalmology

Shantha JG, Yeh S, Nguyen QD

Long-term Management of Panuveitis and Iris Heterochromia in an Ebola Survivor.

Ophthalmology

Shantha JG, Crozier I, Varkey JB, Kraft CS, Lyon GM, Mehta AK, Carlson RD, Hill CE, Kumar G, Debiec MR, Patel PS, Olsen TW, Nussenblatt RB, Martin DF, Ströher U, Uyeki TM, Ribner BS, Smith JR, Yeh S

En Face Spectral-Domain Optical Coherence Tomography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy.

Ophthalmic surgery, lasers & imaging retina

Kokame GT, Shantha JG, Hirai K, Ayabe J

Choroidal Neovascularization Associated With Birdshot Chorioretinopathy.

Ophthalmic surgery, lasers & imaging retina

Shantha JG, Ho VY, Patel P, Forooghian F, Yeh S

Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study.

The Lancet. Infectious diseases

Mattia JG, Vandy MJ, Chang JC, Platt DE, Dierberg K, Bausch DG, Brooks T, Conteh S, Crozier I, Fowler RA, Kamara AP, Kang C, Mahadevan S, Mansaray Y, Marcell L, McKay G, O'Dempsey T, Parris V, Pinto R, Rangel A, Salam AP, Shantha J, Wolfman V, Yeh S, Chan AK, Mishra S

Secondary Vitreoretinal Lymphoma Masquerading as Acute Retinal Necrosis.

Ophthalmic surgery, lasers & imaging retina

Ryan ME, Shantha JG, Grossniklaus HE, Yeh S

Persistence of Ebola Virus in Ocular Fluid during Convalescence.

The New England journal of medicine

Varkey JB, Shantha JG, Crozier I, Kraft CS, Lyon GM, Mehta AK, Kumar G, Smith JR, Kainulainen MH, Whitmer S, Ströher U, Uyeki TM, Ribner BS, Yeh S

Advances in the management of acute retinal necrosis.

International ophthalmology clinics

Shantha JG, Weissman HM, Debiec MR, Albini TA, Yeh S

Emerging causes of viral-associated uveitis.

International ophthalmology clinics

Connors DB, Shantha JG, Yeh S

Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting.

American journal of ophthalmology

Yen M, Chen J, Ausayakhun S, Kunavisarut P, Vichitvejpaisal P, Ausayakhun S, Jirawison C, Shantha J, Holland GN, Heiden D, Margolis TP, Keenan JD

American Society of Ophthalmic Plastic and Reconstructive Surgery fellowship survey: fellows selection criteria for training programs.

Ophthalmic plastic and reconstructive surgery

Shantha JG, Shulman B, Gonzalez M, Hink EM, Durairaj VD

Bilateral proptosis as initial manifestation of mantle cell lymphoma.

The American journal of medicine

Walia SS, Stelton CR, Shantha JG, Connors DB, Walia HS

CD4 count is predictive of outcome in HIV-positive patients undergoing abdominal operations.

American journal of surgery

Deneve JL, Shantha JG, Page AJ, Wyrzykowski AD, Rozycki GS, Feliciano DV